Regulated lysosomal exocytosis mediates cancer progression

Understanding how tumor cells transition to an invasive and drug-resistant phenotype is central to cancer biology, but the mechanisms underlying this transition remain unclear. We show that sarcomas gain these malignant traits by inducing lysosomal exocytosis, a ubiquitous physiological process. Dur...

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Опубликовано в: :Sci Adv
Главные авторы: Machado, Eda, White-Gilbertson, Shai, van de Vlekkert, Diantha, Janke, Laura, Moshiach, Simon, Campos, Yvan, Finkelstein, David, Gomero, Elida, Mosca, Rosario, Qiu, Xiaohui, Morton, Christopher L., Annunziata, Ida, d’Azzo, Alessandra
Формат: Artigo
Язык:Inglês
Опубликовано: American Association for the Advancement of Science 2015
Предметы:
Research Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4730843/
https://ncbi.nlm.nih.gov/pubmed/26824057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1500603
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