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Neuraminidase 1 is a Negative Regulator of Lysosomal Exocytosis

Lysosomal exocytosis is a Ca(2+)-regulated mechanism that involves proteins responsible for cytoskeletal attachment and fusion of lysosomes with the plasma membrane. However, whether luminal lysosomal enzymes contribute to this process remains unknown. Here we show that neuraminidase Neu1 negatively...

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Détails bibliographiques
Auteurs principaux: Yogalingam, Gouri, Bonten, Erik J., van de Vlekkert, Diantha, Hu, Huimin, Moshiach, Simon, Connell, Samuel A., d’Azzo, Alessandra
Format: Artigo
Langue:Inglês
Publié: 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2664108/
https://ncbi.nlm.nih.gov/pubmed/18606142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2008.05.005
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