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Congenic Mice Provide In Vivo Evidence for a Genetic Locus that Modulates Intrinsic TGF-b1-mediated Signaling and Bone Acquisition

Osteoporosis, the most common skeletal disorder, is characterized by low bone mineral density (BMD) and an increased risk of fragility fractures. BMD is the best clinical predictor of future osteoporotic fracture risk, but is a complex trait controlled by multiple environmental and genetic determina...

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Detalhes bibliográficos
Publicado no:J Bone Miner Res
Main Authors: Mukherjee, Aditi, Larson, Emily A., Carlos, Amy S., Belknap, John K., Rotwein, Peter, Klein, Robert F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4729561/
https://ncbi.nlm.nih.gov/pubmed/22407846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.1590
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