Established Stem Cell Model of Spinal Muscular Atrophy Is Applicable in the Evaluation of the Efficacy of Thyrotropin-Releasing Hormone Analog

Spinal muscular atrophy (SMA) is an autosomal recessive neuromuscular disorder characterized by the degeneration of spinal motor neurons. This disease is mainly caused by mutation or deletion of the survival motor neuron 1 (SMN1) gene. Currently, no effective treatment is available, and only symptom...

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Detalhes bibliográficos
Publicado no:Stem Cells Transl Med
Main Authors: Ohuchi, Kazuki, Funato, Michinori, Kato, Zenichiro, Seki, Junko, Kawase, Chizuru, Tamai, Yuya, Ono, Yoko, Nagahara, Yuki, Noda, Yasuhiro, Kameyama, Tsubasa, Ando, Shiori, Tsuruma, Kazuhiro, Shimazawa, Masamitsu, Hara, Hideaki, Kaneko, Hideo
Formato: Artigo
Idioma:Inglês
Publicado em: AlphaMed Press 2016
Assuntos:
Cell-Based Drug Development, Screening, and Toxicology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4729546/
https://ncbi.nlm.nih.gov/pubmed/26683872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5966/sctm.2015-0059
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