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Notch Signaling Mediates Astrocyte Abnormality in Spinal Muscular Atrophy Model Systems
Spinal muscular atrophy (SMA) is an autosomal recessive neuromuscular disorder characterized by the degeneration of spinal motor neurons and muscle atrophy. The disease is mainly caused by low level of the survival motor neuron (SMN) protein, which is coded by two genes, namely SMN1 and SMN2, but le...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6403369/ https://ncbi.nlm.nih.gov/pubmed/30842449 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-39788-w |
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