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Fanconi anemia pathway defects in inherited and sporadic cancers

Fanconi anemia (FA) is a recessive chromosomal instability syndrome. It is a hereditary disorder with defects in DNA repair characterized by progressive bone marrow failure, variable congenital malformations and predisposition to develop hematological or solid tumors. Bi-allelic gene mutations in FA...

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Detalhes bibliográficos
Publicado no:Transl Pediatr
Main Authors: Chen, Hong, Zhang, Shuxia, Wu, Zhanhe
Formato: Artigo
Idioma:Inglês
Publicado em: AME Publishing Company 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4728841/
https://ncbi.nlm.nih.gov/pubmed/26835350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3978/j.issn.2224-4336.2014.07.05
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