Rho Kinase Inhibition as a Therapeutic for Progressive Supranuclear Palsy and Corticobasal Degeneration

Progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD) are neurodegenerative four-repeat tauopathies with no cure. Mitigating pathogenic tau levels is a rational strategy for tauopathy treatment, but therapeutic targets with clinically available drugs are lacking. Here, we report t...

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Detaylı Bibliyografya
Yayımlandı:J Neurosci
Asıl Yazarlar: Gentry, Erik G., Henderson, Benjamin W., Arrant, Andrew E., Gearing, Marla, Feng, Yangbo, Riddle, Nicole C., Herskowitz, Jeremy H.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Society for Neuroscience 2016
Konular:
Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4728727/
https://ncbi.nlm.nih.gov/pubmed/26818518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2336-15.2016
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