Rho Kinase Inhibition as a Therapeutic for Progressive Supranuclear Palsy and Corticobasal Degeneration

Progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD) are neurodegenerative four-repeat tauopathies with no cure. Mitigating pathogenic tau levels is a rational strategy for tauopathy treatment, but therapeutic targets with clinically available drugs are lacking. Here, we report t...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Gentry, Erik G., Henderson, Benjamin W., Arrant, Andrew E., Gearing, Marla, Feng, Yangbo, Riddle, Nicole C., Herskowitz, Jeremy H.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2016
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4728727/
https://ncbi.nlm.nih.gov/pubmed/26818518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2336-15.2016
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