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Reactive Oxygen Species as Additional Determinants for Cytotoxicity of Clostridium difficile Toxins A and B

Clostridium difficile infections can induce mild to severe diarrhoea and the often associated characteristic pseudomembranous colitis. Two protein toxins, the large glucosyltransferases TcdA and TcdB, are the main pathogenicity factors that can induce all clinical symptoms in animal models. The clas...

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Detalhes bibliográficos
Publicado no:Toxins (Basel)
Main Authors: Frädrich, Claudia, Beer, Lara-Antonia, Gerhard, Ralf
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4728547/
https://ncbi.nlm.nih.gov/pubmed/26797634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins8010025
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