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Stepwise B-cell-dependent expansion of T helper clonotypes diversifies the T-cell response
Antigen receptor diversity underpins adaptive immunity by providing the ground for clonal selection of lymphocytes with the appropriate antigen reactivity. Current models attribute T cell clonal selection during the immune response to T-cell receptor (TCR) affinity for either foreign or self peptide...
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Publicado no: | Nat Commun |
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Main Authors: | , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4728444/ https://ncbi.nlm.nih.gov/pubmed/26728651 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10281 |
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