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Negative Selection by an Endogenous Retrovirus Promotes a Higher-Avidity CD4(+) T Cell Response to Retroviral Infection

Effective T cell responses can decisively influence the outcome of retroviral infection. However, what constitutes protective T cell responses or determines the ability of the host to mount such responses is incompletely understood. Here we studied the requirements for development and induction of C...

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Bibliographische Detailangaben
Hauptverfasser: Young, George R., Ploquin, Mickaël J.-Y., Eksmond, Urszula, Wadwa, Munisch, Stoye, Jonathan P., Kassiotis, George
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3349761/
https://ncbi.nlm.nih.gov/pubmed/22589728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002709
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