The high frequency relationship: implications for torsadogenic hERG blockers

BACKGROUND AND PURPOSE: Ventricular arrhythmias induced by human ether‐a‐go‐go related gene (hERG; K(v)11.1 channel) blockers are a consequence of alterations in ventricular repolarisation in association with high‐frequency (HF) oscillations, which act as a primary trigger; the autonomic nervous sys...

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Detaylı Bibliyografya
Yayımlandı:Br J Pharmacol
Asıl Yazarlar: Champeroux, P, Le Guennec, J Y, Jude, S, Laigot, C, Maurin, A, Sola, M L, Fowler, J S L, Richard, S, Thireau, J
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2016
Konular:
Research Papers
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4728413/
https://ncbi.nlm.nih.gov/pubmed/26589499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13391
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