Activating mutations in CTNNB1 in aldosterone producing adenomas

Primary aldosteronism (PA) is the most common cause of secondary hypertension with a prevalence of 5–10% in unreferred hypertensive patients. Aldosterone producing adenomas (APAs) constitute a large proportion of PA cases and represent a surgically correctable form of the disease. The WNT signaling...

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Publicat a:Sci Rep
Autors principals: Åkerström, Tobias, Maharjan, Rajani, Sven Willenberg, Holger, Cupisti, Kenko, Ip, Julian, Moser, Ana, Stålberg, Peter, Robinson, Bruce, Alexander Iwen, K., Dralle, Henning, Walz, Martin K., Lehnert, Hendrik, Sidhu, Stan, Gomez-Sanchez, Celso, Hellman, Per, Björklund, Peyman
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4728393/
https://ncbi.nlm.nih.gov/pubmed/26815163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep19546
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