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RNA Sequencing Provides Novel Insights into the Transcriptome of Aldosterone Producing Adenomas

Aldosterone producing adenomas (APAs) occur in the adrenal glands of around 30% of patients with primary aldosteronism, the most common form of secondary hypertension. Somatic mutations in KCNJ5, ATP1A1, ATP2B3, CACNA1D and CTNNB1 have been described in ~60% of these tumours. We subjected 15 aldoste...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Backman, Samuel, Åkerström, Tobias, Maharjan, Rajani, Cupisti, Kenko, Willenberg, Holger S., Hellman, Per, Björklund, Peyman
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6472367/
https://ncbi.nlm.nih.gov/pubmed/31000732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-41525-2
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