A modified choline-deficient, ethionine-supplemented diet reduces morbidity and retains a liver progenitor cell response in mice

The choline-deficient, ethionine-supplemented (CDE) dietary model induces chronic liver damage, and stimulates liver progenitor cell (LPC)-mediated repair. Long-term CDE administration leads to hepatocellular carcinoma in rodents and lineage-tracing studies show that LPCs differentiate into function...

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Библиографические подробности
Опубликовано в: :Dis Model Mech
Главные авторы: Passman, Adam M., Strauss, Robyn P., McSpadden, Sarah B., Finch-Edmondson, Megan L., Woo, Ken H., Diepeveen, Luke A., London, Roslyn, Callus, Bernard A., Yeoh, George C.
Формат: Artigo
Язык:Inglês
Опубликовано: The Company of Biologists 2015
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Resource Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4728320/
https://ncbi.nlm.nih.gov/pubmed/26496771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.022020
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