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Drugging PI3K in cancer: refining targets and therapeutic strategies
The phosphatidylinositol-3 kinase (PI3K) pathway is one of the most frequently activated pathogenic signalling routes in human cancers, making it a rational and important target for innovative anticancer drug development and precision medicine. The three main classes of PI3K inhibitors currently in...
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| Publié dans: | Curr Opin Pharmacol |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Elsevier Science Ltd
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4728196/ https://ncbi.nlm.nih.gov/pubmed/26117819 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coph.2015.05.016 |
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