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Pharmacological targeting of PI3K isoforms as a therapeutic strategy in chronic lymphocytic leukaemia

PI3Kδ inhibitors such as idelalisib are providing improved therapeutic options for the treatment of chronic lymphocytic leukaemia (CLL). However under certain conditions, inhibition of a single PI3K isoform can be compensated by the other PI3K isoforms, therefore PI3K inhibitors which target multipl...

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Detaylı Bibliyografya
Yayımlandı:Leuk Res Rep
Asıl Yazarlar: Blunt, Matthew D., Steele, Andrew J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4588368/
https://ncbi.nlm.nih.gov/pubmed/26500849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.lrr.2015.09.001
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