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Pharmacological targeting of PI3K isoforms as a therapeutic strategy in chronic lymphocytic leukaemia
PI3Kδ inhibitors such as idelalisib are providing improved therapeutic options for the treatment of chronic lymphocytic leukaemia (CLL). However under certain conditions, inhibition of a single PI3K isoform can be compensated by the other PI3K isoforms, therefore PI3K inhibitors which target multipl...
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| 發表在: | Leuk Res Rep |
|---|---|
| Main Authors: | , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Elsevier
2015
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4588368/ https://ncbi.nlm.nih.gov/pubmed/26500849 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.lrr.2015.09.001 |
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