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Alternative modulation of protein–protein interactions by small molecules

Protein–protein interactions (PPI) have become increasingly popular drug targets, with a number of promising compounds currently in clinical trials. Recent research shows, that PPIs can be modulated in more ways than direct inhibition, where novel non-competitive modes of action promise a solution f...

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Podrobná bibliografie
Vydáno v:Curr Opin Biotechnol
Hlavní autoři: Fischer, Gerhard, Rossmann, Maxim, Hyvönen, Marko
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4728186/
https://ncbi.nlm.nih.gov/pubmed/25935873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.copbio.2015.04.006
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