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Identification of a small molecule HIV-1 inhibitor that targets the capsid hexamer

The HIV-1 CA protein is an attractive therapeutic target for the development of new antivirals. An inter-protomer pocket within the hexamer configuration of the CA, which is a binding site for key host dependency factors, is an especially appealing region for small molecule targeting. Using a field-...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Bioorg Med Chem Lett
Egile Nagusiak: Xu, Jimmy P., Branson, Jeffrey D., Lawrence, Rae, Cocklin, Simon
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4728034/
https://ncbi.nlm.nih.gov/pubmed/26747394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2015.12.087
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