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Simultaneous delivery of cytotoxic and biologic therapeutics using nanophotoactivatable liposomes enhances treatment efficacy in a mouse model of pancreatic cancer

A lack of intracellular delivery systems has limited the use of biologics such as monoclonal antibodies (mAb) that abrogate molecular signaling pathways activated to promote escape from cancer treatment. We hypothesized that intracellular co-delivery of the photocytotoxic chromophore benzoporphyrin...

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Detalles Bibliográficos
Publicado en:Nanomedicine
Main Authors: Tangutoori, Shifalika, Spring, Bryan Q., Mai, Zhiming, Palanisami, Akilan, Mensah, Lawrence, Hasan, Tayyaba
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4728029/
https://ncbi.nlm.nih.gov/pubmed/26390832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2015.08.007
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