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Efficient measurement of total tumor microvascularity ex vivo using a mathematical model to optimize volume subsampling

We introduce immunofluorescence and automated image processing protocols for serial tumor sections to objectively and efficiently quantify tumor microvasculature following antivascular therapy. To determine the trade-off between tumor subsampling and throughput versus microvessel quantification accu...

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Detalhes bibliográficos
Main Authors: Spring, Bryan Q., Palanisami, Akilan, Zheng, Lei Zak, Blatt, Amy E., Bryan Sears, R., Hasan, Tayyaba
Formato: Artigo
Idioma:Inglês
Publicado em: Society of Photo-Optical Instrumentation Engineers 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3783040/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1117/1.JBO.18.9.096015
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