Rapamycin Prevents Bronchiolitis Obliterans through Increasing Regulatory B Cells Infiltration in A Murine Tracheal Transplantation Model

OBJECTIVE: B lymphocytes are generally considered to be activators of the immune response, However recent findings have shown that a subtype of B-lymphocytes, regulatory B lymphocytes (Bregs) play a role in attenuating the immune response. Bronchiolitis obliterans (BO) remains the major limitation t...

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Veröffentlicht in:J Thorac Cardiovasc Surg
Hauptverfasser: Yunge, Zhao, Gillen, Jacob R., Meher, Akshaya K., Burns, Jordan A., Kron, Irving L., Lau, Christine L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4728002/
https://ncbi.nlm.nih.gov/pubmed/26481278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtcvs.2015.08.116
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