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Short-course Rapamycin Treatment Preserves Airway Epithelium and Protects Against Bronchiolitis Obliterans

BACKGROUND: Damage to airway epithelium is closely related to the development of bronchiolitis obliterans (BO) in pulmonary transplantation. Rapamycin protects against BO development in a murine model, but its use in lung transplant patients is limited by its side effects. We hypothesized that short...

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Detalhes bibliográficos
Main Authors: Gillen, Jacob R., Zhao, Yunge, Harris, David A., LaPar, Damien J., Kron, Irving L., Lau, Christine L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3886804/
https://ncbi.nlm.nih.gov/pubmed/23806229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.athoracsur.2013.04.068
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