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Assessing the iron delivery efficacy of transferrin in clinical samples by native electrospray ionization mass spectrometry

Serum transferrin is a key player in iron homeostasis, and its ability to deliver iron to cells via the endosomal pathway critically depends on the presence of carbonate that binds this protein synergistically with ferric ion. Oxalate is another ubiquitous anionic species that can act as a synergist...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Analyst
Prif Awduron: Pawlowski, Jake W., Kellicker, Noelle, Bobst, Cedric E., Kaltashov, Igor A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4727994/
https://ncbi.nlm.nih.gov/pubmed/26646585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5an02159f
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