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Assessing the iron delivery efficacy of transferrin in clinical samples by native electrospray ionization mass spectrometry

Serum transferrin is a key player in iron homeostasis, and its ability to deliver iron to cells via the endosomal pathway critically depends on the presence of carbonate that binds this protein synergistically with ferric ion. Oxalate is another ubiquitous anionic species that can act as a synergist...

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Publicat a:Analyst
Autors principals: Pawlowski, Jake W., Kellicker, Noelle, Bobst, Cedric E., Kaltashov, Igor A.
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4727994/
https://ncbi.nlm.nih.gov/pubmed/26646585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5an02159f
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