Dual-therapy with α(v)β(3)-targeted Sn2 lipase-labile Fumagillin-prodrug Nanoparticles and Zoledronic Acid in the Vx2 Rabbit Tumor Model

Fumagillin, an unstable anti-angiogenesis mycotoxin, was synthesized into a stable lipase-labile prodrug and incorporated into integrin-targeted lipid-encapsulated nanoparticles (α(v)β(3)-Fum-PD NP). Dual anti-angiogenic therapy combining α(v)β(3)-Fum-PD NP with zoledronic acid (ZA), a long-acting o...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Izdano u:Nanomedicine
Glavni autori: Esser, Alison K., Schmieder, Anne H., Ross, Michael H., Xiang, Jingyu, Su, Xinming, Cui, Grace, Zhang, Huiying, Yang, Xiaoxia, Allen, John S., Williams, Todd, Wickline, Samuel A., Pan, Dipanjan, Lanza, Gregory M., Weilbaecher, Katherine N.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4727985/
https://ncbi.nlm.nih.gov/pubmed/26515754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2015.10.003
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items