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The Cyclin-Dependent Kinase Inhibitor SCH 727965 (Dinacliclib) Induces the Apoptosis of Osteosarcoma Cells

Although rare, osteosarcoma is an aggressive cancer that often metastasizes to the lungs. Toward the goal of developing new treatment options for osteosarcoma, we show that the cyclin-dependent kinase (CDK) inhibitor SCH 727965 (SCH) induces the apoptosis of several osteosarcoma cell lines including...

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Detalhes bibliográficos
Publicado no:Mol Cancer Ther
Main Authors: Fu, Wei, Ma, Le, Chu, Baoky, Wang, Xue, Bui, Marilyn M., Gemmer, Jennifer, Altiok, Soner, Pledger, W. Jackson
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4727401/
https://ncbi.nlm.nih.gov/pubmed/21490307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-11-0167
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