Glucocorticoid Clearance and Metabolite Profiling in an In Vitro Human Airway Epithelium Lung Model

The emergence of microphysiologic epithelial lung models using human cells in a physiologically relevant microenvironment has the potential to be a powerful tool for preclinical drug development and to improve predictive power regarding in vivo drug clearance. In this study, an in vitro model of the...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Drug Metab Dispos
Päätekijät: Rivera-Burgos, Dinelia, Sarkar, Ujjal, Lever, Amanda R., Avram, Michael J., Coppeta, Jonathan R., Wishnok, John S., Borenstein, Jeffrey T., Tannenbaum, Steven R.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The American Society for Pharmacology and Experimental Therapeutics 2016
Aiheet:
Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4727117/
https://ncbi.nlm.nih.gov/pubmed/26586376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.115.066365
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