Essential role of proteasomes in maintaining self-renewal in neural progenitor cells

Protein turnover and homeostasis are regulated by the proteasomal system, which is critical for cell function and viability. Pluripotency of stem cells also relies on normal proteasomal activity that mitigates senescent phenotypes induced by intensive cell replications, as previously demonstrated in...

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Udgivet i:Sci Rep
Main Authors: Zhao, Yunhe, Liu, Xueqin, He, Zebin, Niu, Xiaojie, Shi, Weijun, Ding, Jian M., Zhang, Li, Yuan, Tifei, Li, Ang, Yang, Wulin, Lu, Li
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4726439/
https://ncbi.nlm.nih.gov/pubmed/26804982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep19752
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