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Essential role of proteasomes in maintaining self-renewal in neural progenitor cells

Protein turnover and homeostasis are regulated by the proteasomal system, which is critical for cell function and viability. Pluripotency of stem cells also relies on normal proteasomal activity that mitigates senescent phenotypes induced by intensive cell replications, as previously demonstrated in...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Zhao, Yunhe, Liu, Xueqin, He, Zebin, Niu, Xiaojie, Shi, Weijun, Ding, Jian M., Zhang, Li, Yuan, Tifei, Li, Ang, Yang, Wulin, Lu, Li
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4726439/
https://ncbi.nlm.nih.gov/pubmed/26804982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep19752
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