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Essential role of proteasomes in maintaining self-renewal in neural progenitor cells

Protein turnover and homeostasis are regulated by the proteasomal system, which is critical for cell function and viability. Pluripotency of stem cells also relies on normal proteasomal activity that mitigates senescent phenotypes induced by intensive cell replications, as previously demonstrated in...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zhao, Yunhe, Liu, Xueqin, He, Zebin, Niu, Xiaojie, Shi, Weijun, Ding, Jian M., Zhang, Li, Yuan, Tifei, Li, Ang, Yang, Wulin, Lu, Li
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4726439/
https://ncbi.nlm.nih.gov/pubmed/26804982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep19752
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