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Mesenchymal stem cells maintain their defining stem cell characteristics after treatment with cisplatin

Mesenchymal stem cells (MSCs) aid the regeneration of tissues damaged by treatment with cisplatin. However, the effects of this cytotoxic drug on the stem cells have been largely unknown. Here we demonstrate that human bone marrow-derived MSCs are relatively resistant to cisplatin treatment and show...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Nicolay, Nils H., Perez, Ramon Lopez, Rühle, Alexander, Trinh, Thuy, Sisombath, Sonevisay, Weber, Klaus-Josef, Ho, Anthony D., Debus, Jürgen, Saffrich, Rainer, Huber, Peter E.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4726328/
https://ncbi.nlm.nih.gov/pubmed/26805490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep20035
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