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Human mesenchymal stem cells lose their functional properties after paclitaxel treatment

Mesenchymal stem cells (MSCs) are an integral part of the bone marrow niche and aid in the protection, regeneration and proliferation of hematopoietic stem cells after exposure to myelotoxic taxane anti-cancer agents, but the influence of taxane compounds on MSCs themselves remains incompletely unde...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Münz, Franziska, Lopez Perez, Ramon, Trinh, Thuy, Sisombath, Sonevisay, Weber, Klaus-Josef, Wuchter, Patrick, Debus, Jürgen, Saffrich, Rainer, Huber, Peter E., Nicolay, Nils H.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5762916/
https://ncbi.nlm.nih.gov/pubmed/29321693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-18862-1
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