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Mesenchymal stem cells maintain their defining stem cell characteristics after treatment with cisplatin

Mesenchymal stem cells (MSCs) aid the regeneration of tissues damaged by treatment with cisplatin. However, the effects of this cytotoxic drug on the stem cells have been largely unknown. Here we demonstrate that human bone marrow-derived MSCs are relatively resistant to cisplatin treatment and show...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Nicolay, Nils H., Perez, Ramon Lopez, Rühle, Alexander, Trinh, Thuy, Sisombath, Sonevisay, Weber, Klaus-Josef, Ho, Anthony D., Debus, Jürgen, Saffrich, Rainer, Huber, Peter E.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4726328/
https://ncbi.nlm.nih.gov/pubmed/26805490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep20035
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