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Mechanism of substrate recognition by the novel Botulinum Neurotoxin subtype F5

Botulinum Neurotoxins (BoNTs) are the causative agents of botulism, which act by potently inhibiting the neurotransmitter release in motor neurons. Seven serotypes of BoNTs designated as BoNT/A-G have been identified. Recently, two novel types of Botulinum neurotoxins, which cleave a novel scissile...

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Pubblicato in:Sci Rep
Autori principali: Guo, Jiubiao, Chan, Edward Wai Chi, Chen, Sheng
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4726221/
https://ncbi.nlm.nih.gov/pubmed/26794648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep19875
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