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Unique Substrate Recognition Mechanism of the Botulinum Neurotoxin D Light Chain

Botulinum neurotoxins are the most potent protein toxins in nature. Despite the potential to block neurotransmitter release at the neuromuscular junction and cause human botulism, they are widely used in protein therapies. Among the seven botulinum neurotoxin serotypes, mechanisms of substrate recog...

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Autors principals: Guo, Jiubiao, Chen, Sheng
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3784703/
https://ncbi.nlm.nih.gov/pubmed/23963459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.491134
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