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Conversion of embryonic stem cells into extraembryonic lineages by CRISPR-mediated activators
The recently emerged CRISPR/Cas9 technique has opened a new perspective on readily editing specific genes. When combined with transcription activators, it can precisely manipulate endogenous gene expression. Here, we enhanced the expression of endogenous Cdx2 and Gata6 genes by CRISPR-mediated activ...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4726097/ https://ncbi.nlm.nih.gov/pubmed/26782778 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep19648 |
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