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Conversion of embryonic stem cells into extraembryonic lineages by CRISPR-mediated activators
The recently emerged CRISPR/Cas9 technique has opened a new perspective on readily editing specific genes. When combined with transcription activators, it can precisely manipulate endogenous gene expression. Here, we enhanced the expression of endogenous Cdx2 and Gata6 genes by CRISPR-mediated activ...
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| 出版年: | Sci Rep |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4726097/ https://ncbi.nlm.nih.gov/pubmed/26782778 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep19648 |
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