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Structural Elucidation of a Carnosine-Acrolein Adduct and its Quantification in Human Urine Samples

Aldehydes accumulate in inflammation, during myocardial infarction and have been associated with pain symptoms. One pathway of aldehyde detoxification is the conjugation with carnosine. A 3-methylpyridinium carnosine adduct from the reaction of carnosine and acrolein was characterized using extensiv...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Bispo, Vanderson S., de Arruda Campos, Ivan P., Di Mascio, Paolo, Medeiros, Marisa H. G.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4726056/
https://ncbi.nlm.nih.gov/pubmed/26783107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep19348
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