Structural Elucidation of a Carnosine-Acrolein Adduct and its Quantification in Human Urine Samples

Aldehydes accumulate in inflammation, during myocardial infarction and have been associated with pain symptoms. One pathway of aldehyde detoxification is the conjugation with carnosine. A 3-methylpyridinium carnosine adduct from the reaction of carnosine and acrolein was characterized using extensiv...

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Published in:Sci Rep
Main Authors: Bispo, Vanderson S., de Arruda Campos, Ivan P., Di Mascio, Paolo, Medeiros, Marisa H. G.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4726056/
https://ncbi.nlm.nih.gov/pubmed/26783107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep19348
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