Focal Adhesion Kinase Regulates Fibroblast Migration via Integrin beta-1 and Plays a Central Role in Fibrosis

Lung fibrosis is a major medical problem for the aging population worldwide. Fibroblast migration plays an important role in fibrosis. Focal Adhesion Kinase (FAK) senses the extracellular stimuli and initiates signaling cascades that promote cell migration. This study first examined the dose and tim...

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Udgivet i:Sci Rep
Main Authors: Zhao, Xue-Ke, Cheng, Yiju, Liang Cheng, Ming, Yu, Lei, Mu, Mao, Li, Hong, Liu, Yang, Zhang, Baofang, Yao, Yumei, Guo, Hui, Wang, Rong, Zhang, Quan
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4725867/
https://ncbi.nlm.nih.gov/pubmed/26763945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep19276
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