טוען...
Mechanism of FGF receptor dimerization and activation
Fibroblast growth factors (fgfs) are widely believed to activate their receptors by mediating receptor dimerization. Here we show, however, that the FGF receptors form dimers in the absence of ligand, and that these unliganded dimers are phosphorylated. We further show that ligand binding triggers s...
שמור ב:
| הוצא לאור ב: | Nat Commun |
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| Main Authors: | , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Nature Publishing Group
2016
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4725768/ https://ncbi.nlm.nih.gov/pubmed/26725515 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10262 |
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