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Targeted modulation of cell differentiation in distinct regions of the gastrointestinal tract via oral administration of differently PEG-PEI functionalized mesoporous silica nanoparticles

Targeted delivery of drugs is required to efficiently treat intestinal diseases such as colon cancer and inflammation. Nanoparticles could overcome challenges in oral administration caused by drug degradation at low pH and poor permeability through mucus layers, and offer targeted delivery to diseas...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Int J Nanomedicine
Hauptverfasser: Desai, Diti, Prabhakar, Neeraj, Mamaeva, Veronika, Karaman, Didem Şen, Lähdeniemi, Iris AK, Sahlgren, Cecilia, Rosenholm, Jessica M, Toivola, Diana M
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove Medical Press 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4725644/
https://ncbi.nlm.nih.gov/pubmed/26855569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S94013
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