Mesoporous Silica Nanoparticles as Drug Delivery Systems for Targeted Inhibition of Notch Signaling in Cancer

Notch signaling, a key regulator of stem cells, is frequently overactivated in cancer. It is often linked to aggressive forms of cancer, evading standard treatment highlighting Notch as an exciting therapeutic target. Notch is in principle “druggable” by γ-secretase inhibitors (GSIs), inhibitory pep...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Mamaeva, Veronika, Rosenholm, Jessica M, Bate-Eya, Laurel Tabe, Bergman, Lotta, Peuhu, Emilia, Duchanoy, Alain, Fortelius, Lina E, Landor, Sebastian, Toivola, Diana M, Lindén, Mika, Sahlgren, Cecilia
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2011
Onderwerpen:
Original Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149161/
https://ncbi.nlm.nih.gov/pubmed/21629222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.105
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items