Mesoporous Silica Nanoparticles as Drug Delivery Systems for Targeted Inhibition of Notch Signaling in Cancer

Notch signaling, a key regulator of stem cells, is frequently overactivated in cancer. It is often linked to aggressive forms of cancer, evading standard treatment highlighting Notch as an exciting therapeutic target. Notch is in principle “druggable” by γ-secretase inhibitors (GSIs), inhibitory pep...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Mamaeva, Veronika, Rosenholm, Jessica M, Bate-Eya, Laurel Tabe, Bergman, Lotta, Peuhu, Emilia, Duchanoy, Alain, Fortelius, Lina E, Landor, Sebastian, Toivola, Diana M, Lindén, Mika, Sahlgren, Cecilia
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2011
Gaiak:
Original Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149161/
https://ncbi.nlm.nih.gov/pubmed/21629222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.105
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