Mesoporous Silica Nanoparticles as Drug Delivery Systems for Targeted Inhibition of Notch Signaling in Cancer

Notch signaling, a key regulator of stem cells, is frequently overactivated in cancer. It is often linked to aggressive forms of cancer, evading standard treatment highlighting Notch as an exciting therapeutic target. Notch is in principle “druggable” by γ-secretase inhibitors (GSIs), inhibitory pep...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Mamaeva, Veronika, Rosenholm, Jessica M, Bate-Eya, Laurel Tabe, Bergman, Lotta, Peuhu, Emilia, Duchanoy, Alain, Fortelius, Lina E, Landor, Sebastian, Toivola, Diana M, Lindén, Mika, Sahlgren, Cecilia
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149161/
https://ncbi.nlm.nih.gov/pubmed/21629222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.105
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados