Feasibility Study of the Permeability and Uptake of Mesoporous Silica Nanoparticles across the Blood-Brain Barrier

Drug delivery into the brain is impeded by the blood-brain-barrier (BBB) that filters out the vast majority of drugs after systemic administration. In this work, we assessed the transport, uptake and cytotoxicity of promising drug nanocarriers, mesoporous silica nanoparticles (MSNs), in in vitro mod...

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Publicado en:PLoS One
Autores principales: Baghirov, Habib, Karaman, Didem, Viitala, Tapani, Duchanoy, Alain, Lou, Yan-Ru, Mamaeva, Veronika, Pryazhnikov, Evgeny, Khiroug, Leonard, de Lange Davies, Catharina, Sahlgren, Cecilia, Rosenholm, Jessica M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2016
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4993362/
https://ncbi.nlm.nih.gov/pubmed/27547955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0160705
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