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Sex-specific silencing of X-linked genes by Xist RNA

X-inactive specific transcript (Xist) long noncoding RNA (lncRNA) is thought to catalyze silencing of X-linked genes in cis during X-chromosome inactivation, which equalizes X-linked gene dosage between male and female mammals. To test the impact of Xist RNA on X-linked gene silencing, we ectopicall...

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Gayen, Srimonta, Maclary, Emily, Hinten, Michael, Kalantry, Sundeep
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4725534/
https://ncbi.nlm.nih.gov/pubmed/26739568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1515971113
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