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Sex-specific silencing of X-linked genes by Xist RNA

X-inactive specific transcript (Xist) long noncoding RNA (lncRNA) is thought to catalyze silencing of X-linked genes in cis during X-chromosome inactivation, which equalizes X-linked gene dosage between male and female mammals. To test the impact of Xist RNA on X-linked gene silencing, we ectopicall...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Gayen, Srimonta, Maclary, Emily, Hinten, Michael, Kalantry, Sundeep
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4725534/
https://ncbi.nlm.nih.gov/pubmed/26739568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1515971113
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