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Combination therapy with bioengineered miR-34a prodrug and doxorubicin synergistically suppresses osteosarcoma growth

Osteosarcoma (OS) is the most common form of primary malignant bone tumor and prevalent among children and young adults. Recently we have established a novel approach to bioengineering large quantity of microRNA-34a (miR-34a) prodrug for miRNA replacement therapy. This study is to evaluate combinati...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Biochem Pharmacol
Päätekijät: Zhao, Yong, Tu, Mei-Juan, Yu, Yi-Feng, Wang, Wei-Peng, Chen, Qiu-Xia, Qiu, Jing-Xin, Yu, Ai-Xi, Yu, Ai-Ming
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4725324/
https://ncbi.nlm.nih.gov/pubmed/26518752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2015.10.015
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