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Combination therapy with bioengineered miR-34a prodrug and doxorubicin synergistically suppresses osteosarcoma growth

Osteosarcoma (OS) is the most common form of primary malignant bone tumor and prevalent among children and young adults. Recently we have established a novel approach to bioengineering large quantity of microRNA-34a (miR-34a) prodrug for miRNA replacement therapy. This study is to evaluate combinati...

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Detalhes bibliográficos
Publicado no:Biochem Pharmacol
Main Authors: Zhao, Yong, Tu, Mei-Juan, Yu, Yi-Feng, Wang, Wei-Peng, Chen, Qiu-Xia, Qiu, Jing-Xin, Yu, Ai-Xi, Yu, Ai-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4725324/
https://ncbi.nlm.nih.gov/pubmed/26518752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2015.10.015
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