Bioengineered miRNA-1291 prodrug therapy in pancreatic cancer cells and patient-derived xenograft mouse models

Our recent studies have revealed that microRNA-1291 (miR-1291) is downregulated in pancreatic cancer (PC) specimens and restoration of miR-1291 inhibits tumorigenesis of PC cells. This study is to assess the efficacy and underlying mechanism of our bioengineered miR-1291 prodrug monotherapy and comb...

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Detalhes bibliográficos
Publicado no:Cancer Lett
Main Authors: Tu, Mei-Juan, Ho, Pui Yan, Zhang, Qian-Yu, Jian, Chao, Qiu, Jing-Xin, Kim, Edward J., Bold, Richard J., Gonzalez, Frank J., Bi, Huichang, Yu, Ai-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6311422/
https://ncbi.nlm.nih.gov/pubmed/30389433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2018.10.038
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