Antitumor effect of afatinib, as a human epidermal growth factor receptor 2‐targeted therapy, in lung cancers harboring HER2 oncogene alterations

Human epidermal growth factor receptor 2 (HER2) is a member of the HER family of proteins containing four receptor tyrosine kinases. It plays an important role in the pathogenesis of certain human cancers. In non‐small‐cell lung cancer (NSCLC), HER2 amplification or mutations have been reported. How...

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Enregistré dans:
Détails bibliographiques
Publié dans:Cancer Sci
Auteurs principaux: Suzawa, Ken, Toyooka, Shinichi, Sakaguchi, Masakiyo, Morita, Mizuki, Yamamoto, Hiromasa, Tomida, Shuta, Ohtsuka, Tomoaki, Watanabe, Mototsugu, Hashida, Shinsuke, Maki, Yuho, Soh, Junichi, Asano, Hiroaki, Tsukuda, Kazunori, Miyoshi, Shinichiro
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2015
Sujets:
Original Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4724821/
https://ncbi.nlm.nih.gov/pubmed/26545934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12845
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